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Without the research of biochemists Katalin Karikó and Drew Weissman, COVID-19 might have never had a cure. The first vaccines against COVID-19 were made possible by modifications of mRNA. More than 13.5 billion COVID-19 vaccines have been administered, mainly from this work. Finally, this year, they have been awarded the Nobel Prize for their research. Their modifications to the virus RNA produced weakened proteins, which, when introduced through vaccines, could initiate an immune response and so prevent a person from getting COVID-19.